Douglas Vaughan, M.D.

Director & Irving S. Cutter Professor of Medicine
Chair, Department of Medicine
Potocsnak Longevity Institute,
Feinberg School of Medicine
Northwestern University
Douglas E. Vaughan, MD
Irving S. Cutter Professor and Chair, Department of Medicine
Director, Potoscnak Longevity Institute
Northwestern University Feinberg School of Medicine
Dr. Vaughan is chairman of the Department of Medicine and the Irving S. Cutter Professor of Medicine in the Division of Cardiology at Northwestern University Feinberg School of Medicine. He is a fellow of the American College of Cardiology and has been elected to membership in the American Society for Clinical Investigation and the Association of American Physicians.

As a principal clinical investigator, Dr. Vaughan spans the bench to the bedside in his work. His efforts and findings in vascular biology include basic investigations into regulation of gene expression, genetic models of disease, mechanistic studies in humans, and clinical trials. His primary research interests are in the mammalian plasminogen activator system and the role this system plays in cardiovascular disease and physiological aging.

In 2018, Dr. Vaughan led a study that reported the first genetic variation that appears to protect against multiple aspects of biological aging in humans in an extended kindred of Old Order Amish living in the vicinity of Berne, Indiana.

Dr. Vaughan now leads the recently launched Potoscnak Longevity Institute, bringing together scientists and experts across many disciplines to study those populations that seem resistant to negative consequences of aging with a goal of discovering what makes them unique. With a deeper understanding of how aging works, the institute aims to expand the healthspan for all people with future therapies and lifestyle interventions.
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